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Therapy vs. Medication for Depression: What Works? Depression doesn’t come with a one-size-fits-all solution. It’s a deeply personal experience—one that affects mood, energy, sleep, appetite, and the ability to function in daily life. When it comes to treatment, most people find themselves stuck between two choices: therapy or medication. So, what actually works? The short answer is: it depends. But let’s unpack that in a meaningful way that goes beyond clinical definitions. Because when you’re